Plausibilities of Recurrence of Sars-Cov-2 in Covid-19 recovered patients and efficacy of antibody therapy for Covid-19: A Review

IRIS                       

Journal for Young Scientists

ISSN 2278-618X (Print)

ISSN 2278-6384 (Online)

© Patna Women’s College, Patna, India

http://www.patnawomenscollege.in/journal

Plausibilities of Recurrence of Sars-Cov-2 in Covid-19 recovered patients and efficacy of antibody therapy for Covid-19: A Review

 • Sharbeen Fatma • Kriti Novel • Muskan • Jaya Philip

Received                  : July, 2022

Accepted                 : August, 2022

Corresponding Author   : Jaya Philip

Abstract: The world has suffered immensely with outbreak of SARS-COV-2 in the end of 2019. Amidst this, some cases of recurrence of SARS-CoV-2 in COVID-19 recovered patients have come forward that seeks attention. In desperate times, before the advent of vaccines for this disease, the health care professionals inclined to an underestimated age-old therapy of antibody transfusion for emergency prophylaxis. The authors have explored various research papers and journals leading with relevant words in online database, independently studying to draw inference and finally converge the gathered information into a review paper. Possible reasons for reinfection incline towards falsely negative results mostly. However, people with comorbidities are

 at a higher risk of reinfection. Viral mutations can also be a cause of reinfection. The underestimated antibody therapy has helped in reducing the symptoms during infection and mitigated the viral replication showing good efficacy. The chances of recurrence are low after recovery. Standardisation of diagnostic tests seeks improvement before discharge from hospital. Post recovery isolation is encouraged. The early transfusion of high titre antibody has been of great help showing effectively low mortality rates.

Keywords: COVID-19, recurrence, reinfection, antibody therapy, antibody.

Sharbeen Fatma

B.Sc. Ill year, Microbiology (Hons.), Session: 2019-2022,

Patna Women’s College (Autonomous),

Patna University, Patna, Bihar, India

Kriti Novel

B.Sc. Ill year, Microbiology (Hons.), Session: 2019-2022,

Patna Women’s College (Autonomous),

Patna University, Patna, Bihar, India

Muskan

B.Sc. III year, Microbiology (Hons.), Session:2019-2022,

Patna Women’s College (Autonomous),

Patna University, Patna, Bihar, India

Jaya Philip

Head., Department of Microbiology,

Patna Women’s College (Autonomous),

Bailey Road, Patna 800001, Bihar, India

E-mail: jaya.mbio@patnawomenscollege.in